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英國(guó)Cyprotex  
Cyprotex是ADME數(shù)據(jù)和藥動(dòng)學(xué)預(yù)測(cè)服務(wù)的專(zhuān)業(yè)供應(yīng)商。該公司特有的Cloe(R)Screen技術(shù)將巧妙的方案與先進(jìn)的自動(dòng)化操作相結(jié)合，使得Cyprotex能夠同時(shí)提供高品質(zhì)、具有成本效益的數(shù)據(jù)和較短的周轉(zhuǎn)時(shí)間。深入地研究需要更加靈活的方案，而Cloe(R)Select的推出確保了Cyprotex能夠?qū)⑵洚a(chǎn)品拓展至深入研究的后期。Cyprotex的Cloe(R)預(yù)測(cè)服務(wù)在生理藥動(dòng)學(xué)(PB-PK)建模和定量構(gòu)效關(guān)系(QSAR)建模技術(shù)領(lǐng)域還擁有全面的專(zhuān)長(zhǎng)。Cloe(R)Screen、Cloe(R)Select和Cloe(R)Predict的結(jié)合為實(shí)驗(yàn)篩選和預(yù)測(cè)提供了一個(gè)綜合解決方案，滿(mǎn)足了該公司龐大且多樣化的客戶(hù)群的需求。

Cyprotex is a world renowned preclinical discovery/development contract research organisation with a core focus
in analysing the ADME (absorption, distribution, metabolism and excretion) and pharmacokinetic properties
of potential new drugs.
Cyprotex is based in Macclesfield, nr. Manchester in the UK and is listed on the AIM market of the London Stock Exchange (CRX). Our company was established in 1999 and we work with in excess of 200 partners ranging from small Biotechs to large Pharma. We provide support for a wide range of experimental and computational ADME and PK services extending from early drug discovery through to IND submission.

Our core capabilities include:

Our unique Cloe? Screen platform which is based on state of the art robotics and a highly sophisticated customised information management system. This dramatically reduces the cost and time in generating data whilst ensuring excellent reproducibility of data.
Our Cloe? Select experimental service which provides support for later stage ADME and DMPK studies.
A range of predictive technologies available under Cloe? Predict which take advantage of our extensive expertise in PBPK and QSAR modelling. Our proprietary Cloe? PK software product integrates core ADME and physicochemical properties to predict whole body pharmacokinetics.